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Zoloft (Sertraline)

Zoloft (Sertraline) is a prescription medicine used to treat depression, panic disorder.

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Product description

Drug Name

Zoloft (Sertraline)

Zoloft Drug Class and Mechanism

Sertraline belongs to a class of drugs called selective serotonin reuptake inhibitors (SSRI). Other drugs in this class are Prozac (fluoxetine), Paxil (paroxetine), Celexa (citalopram) and Luvox (fluvoxamine). Serotonin is a neurotransmitter (a chemical messenger) produced by nerve cells in the brain that is used by the nerves to communicate with one another. A nerve releases the serotonin it produces into the space surrounding it. The serotonin either travels across the space and attaches to receptors on the surface of nearby nerves or it attaches to receptors on the surface of the nerve that produced it, to be taken up by the nerve and released again (a process referred to as re-uptake). A balance is reached for serotonin between attachment to the nearby nerves and reuptake. Selective serotonin inhibitors block the reuptake of serotonin and therefore change the level of serotonin in the brain. It is believed that some illnesses such as depression are caused by disturbances in the balance between serotonin and other neurotransmitters. The leading theory is that drugs such as sertraline restore the chemical balance among neurotransmitters in the brain. Sertraline was approved by the Food and Drug Administration in December, 1991.

Zoloft Drug Uses

Zoloft (Sertraline) is a prescription medicine used to treat depression, panic disorder.

Zoloft Possible Side Effects

If you experience any of the following serious side effects, stop taking Zoloft and contact your doctor immediately or seek emergency medical treatment: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); an irregular heartbeat or pulse; low blood pressure (dizziness, weakness); high blood pressure (severe headache, blurred vision); or chills or fever. If you experience any of the following less serious side effects, continue taking Zoloft and talk to your doctor: headache; tremor, nervousness, or anxiety; nausea, diarrhea, dry mouth, or changes in appetite or weight; sleepiness or insomnia; or decreased sex drive, impotence, or difficulty having an orgasm. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

More Information about Zoloft

If you experience any of the following serious side effects, stop taking sertraline and contact your doctor immediately or seek emergency medical treatment: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); an irregular heartbeat or pulse; low blood pressure (dizziness, weakness); high blood pressure (severe headache, blurred vision); or chills or fever.* If you experience any of the following less serious side effects, continue taking sertraline and talk to your doctor:* headache;* tremor, nervousness, or anxiety;* nausea, diarrhea, dry mouth, or changes in appetite or weight;* sleepiness or insomnia; or* decreased sex drive, impotence, or difficulty having an orgasm.* Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

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